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I know that chemoreceptors regulate blood pressure by monitoring the levels of H, O2 and CO2 in the blood, but why and how do these chemicals effect blood pressure?

I know that if too much CO2 and H is found in the blood by chemoreceptors, the medula oblongata will cause vasodialation (or constriction if there is too little im guessing) along with a slower heart rate. But how and why do these chemicals effect the blood pressure?

Recent scientific research suggests that a problem of the inner lining of blood vessel walls, called the endothelium Singular layer of flat cells that lines the walls of the heart, blood vessels, and lymphatic vessels; inner lining of the tunica intima layer of blood vessels, may contribute to hypertension. Substances released from the endothelium can cause blood vessels to dilate or constrict. Some substances also promote or inhibit growth of the smooth muscle cells in the blood vessel wall.

Normally, the actions of these substances are held in balance. But in some people, the constriction chemicals may overpower the relaxation chemicals. Arteries narrow, and blood pressure goes up because it is more difficult for blood to circulate.

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